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Fat Burning Hormone


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Today on Cheepedy Cheep Heep news, I, CheepHeep, bring you the latest scientific discoveries in hopes to inspire and expand the intellectual side of our young assassins, beyond the scopes of gaming. To keep updated with the latest that the worlds elites offer to us and to increase awareness of the world we love in today.

 

Regular updates on different scientific topics will be brought right to your doorstep here at FA.

 

Enough with the bullcrap cheep. Get on with it....

 

Biologists at The Scripps Research Institute (TSRI) have identified a brain hormone that appears to trigger fat burning in the gut. Their findings in animal models could have implications for future pharmaceutical development.

 

"This was basic science that unlocked an interesting mystery," said TSRI Assistant Professor Supriya Srinivasan, senior author of the new study, published in the journal Nature Communications.

 

Previous studies had shown that the neurotransmitter serotonin can drive fat loss. Yet no one was sure exactly how. To answer that question, Srinivasan and her colleagues experimented with roundworms called C. elegans, which are often used as model organisms in biology. These worms have simpler metabolic systems than humans, but their brains produce many of the same signaling molecules, leading many researchers to believe that findings in C. elegans may be relevant for humans.

 

The researchers deleted genes in C. elegans to see if they could interrupt the path between brain serotonin and fat burning. By testing one gene after another, they hoped to find the gene without which fat burning wouldn't occur. This process of elimination led them to a gene that codes for a neuropeptide hormone they named FLP-7 (pronounced "flip 7").

 

Interestingly, they found that the mammalian version of FLP-7 (called Tachykinin) had been identified 80 years ago as a peptide that triggered muscle contractions when dribbled on pig intestines. Scientists back then believed this was a hormone that connected the brain to the gut, but no one had linked the neuropeptide to fat metabolism in the time since.

 

The next step in the new study was to determine if FLP-7 was directly linked to serotonin levels in the brain. Study first author Lavinia Palamiuc, a TSRI research associate, spearheaded this effort by tagging FLP-7 with a fluorescent red protein so that it could be visualized in living animals, possible because the roundworm body is transparent. Her work revealed that FLP-7 was indeed secreted from neurons in the brain in response to elevated serotonin levels. FLP-7 then traveled through the circulatory system to start the fat burning process in the gut.

 

"That was a big moment for us," said Srinivasan. For the first time, researchers had found a brain hormone that specifically and selectively stimulates fat metabolism, without any effect on food intake.

 

Altogether, the newly discovered fat-burning pathway works like this: a neural circuit in the brain produces serotonin in response to sensory cues, such as food availability. This signals another set of neurons to begin producing FLP-7. FLP-7 then activates a receptor in intestinal cells, and the intestines begin turning fat into energy.

 

Source : Scripps Research Institute.

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I was sure this was going to be another spam topic about fat burning and brain stimulation, pleasant surprise :D

I guess everyone here has a 6 pack and 0% fat. Lol. Except you plat. You're the only that replied. :P

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I´m really skeptical about this research. I´m not the happiest person on planet and I can eat whatever I want and how much I want and still loose in weight. As serotonin is "happiness hormone" it couldn´t be so. And there are examples of vice versa. Just another research "sucked out of a pen"...

 

All the research will lead is probably 3rd boob in teh face- doesn´t matter if it goes about male\females.

 

(Dunno why this fit chica went to the show but anyways). What could work is "salad, fish and water diet": https://youtu.be/xV2QLMy9ESU?t=1m49s

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It is a long way from studies on "roundworms called C. elegans" to human trials.  I believe that most of our DNA guides our biochemistry and not so much the structures of our bodies.  We supposedly share most of our DNA with ants!   :D

 

I have seen the purported results of many single preliminary studies published in the mainstream media over the years. I just imagine millions of people changing their lives based on one study, without waiting for further investigations.  Many people blame side-effects discovered in long-used medications years after their introduction on the "greed" of the pharmaceutical companies.  Others will accept claims by Natural Medicine peddlers without investigating their unscientific sources, nor do they call them greedy.   :)

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The best way to lose fat is to train your body regularly and have a proper low-sugar diet. There's already plenty of serotonin complements and none of them cause weight loss. Now there are some effective weight loss products like amphetamines etc. but they are pretty dangerous for your heart. There's just no magic pill. No pain, no gain ;)

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Cheers ill take a look. Filter out the complicated ones and post the interesting, easy to understand ones for the simpletons that plague our forum like alphaloki.

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im happy person my metabolism is working very fine. when i feel i my weight is "too much", i eat 2-3 days bit less and i lost it again. 

 

i think the best way to loss gain is still, the food u eat (the detox week i just made brought around 2kg less) and sport (i heard at least about that sport thing)

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